Transcriptomic profiling of HIV exposure in infant Treg cells

# Wiki

# Data location

Data is available in the form of compressed fastq files. Approximately 600 GB after unzipping the files. Files are to be uploaded onto the UCT G-drive.

# Bioinformatic analyses requested

Standard RNA sequencing analysis including quality assessment, data normalization, alignment, gene mapping, pairwise comparisons, functional enrichment and visualization.

# Papers envisaged

Data from this analysis will be incorporated in a manuscript phenotyping the changes in immune cells (T regulatory and Th17 cells) during infancy or as a stand-alone manuscript. The authors will include the team in the Clive Gray and Heather Jaspan group involved in this work together with the Bioinfomatician from CBIO who is willing to collaborate with this analysis.