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Support #24

Setting up the NGI-RNAseq pipeline on UCT Hex

Added by Gerrit Botha about 7 years ago. Updated about 7 years ago.

Status:
New
Priority:
Normal
Assignee:
Start date:
04/09/2018
Due date:
% Done:

0%

Estimated time:
(Total: 0.00 h)
Spent time:
(Total: 12.60 h)

Description

Katie received a support request to analyse human RNA-Seq data. We do not have a pipeline ready for just pushing RNA-Seq data through.

We have also seen in the CBIO 2017 bioinformatics needs survey that there are many users interested in RNA-Seq analysis.

To get ready for the Katie's analysis and also doing planning ahead we need to start setting up a portable/robust RNA-Seq pipeline that initially does analysis on human data only. We can look into existing pipelines or develop our own.

Existing pipelines that might get things done

  • https://github.com/SciLifeLab/NGI-RNAseq/ is developed by a bioinformatician that is very active in the Nextflow community. Jon had a look at the pipeline and said it is worth getting it up and running.
  • Jenny Drnevich mentioned that they have a Nextflow pipeline based on the new version of the H3ABioNet RNA-Seq SOP. Might also be worth looking into that. Gerrit can follow up on this.

For now Katie is setting up the NGI-RNAseq pipeline on UCT Hex and will check if we can just use the pipeline as is.


Subtasks

Support #25: Configure NGI-RNAseq pipeline to run on hexIn Progress

Actions
Support #30: Update Nextflow to version 0.27.6In ProgressGerrit Botha

Actions

History

#1

Updated by Gerrit Botha about 7 years ago

Katie I've talked to Chris Fields he is working with Jenny. He will check if he can make their pipeline available. He says it is basically a template from the one that you are currently working but expanded to include Salmon counts and more QC. If he shares the code we can see what he means.

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